Georg Schett Selected Research

apremilast

8/2020	Long-Term Safety and Tolerability of Apremilast Versus Placebo in Psoriatic Arthritis: A Pooled Safety Analysis of Three Phase III, Randomized, Controlled Trials.
10/2019	Long-term experience with apremilast in patients with psoriatic arthritis: 5-year results from a PALACE 1-3 pooled analysis.
1/2018	Therapeutic benefit of apremilast on enthesitis and dactylitis in patients with psoriatic arthritis: a pooled analysis of the PALACE 1-3 studies.
6/2017	Inhibition of phosphodiesterase 4 (PDE4) reduces dermal fibrosis by interfering with the release of interleukin-6 from M2 macrophages.
9/2015	Apremilast in psoriatic arthritis.
3/2015	Longterm (52-week) results of a phase III randomized, controlled trial of apremilast in patients with psoriatic arthritis.
6/2014	Treatment of psoriatic arthritis in a phase 3 randomised, placebo-controlled trial with apremilast, an oral phosphodiesterase 4 inhibitor.
7/2013	Patient-reported Health-related Quality of Life with apremilast for psoriatic arthritis: a phase II, randomized, controlled study.
10/2012	Oral apremilast in the treatment of active psoriatic arthritis: results of a multicenter, randomized, double-blind, placebo-controlled study.
10/2010	Apremilast: a novel PDE4 inhibitor in the treatment of autoimmune and inflammatory diseases.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Georg Schett Research Topics

Disease

112	Inflammation (Inflammations) 01/2022 - 03/2002
92	Rheumatoid Arthritis 10/2022 - 11/2002
88	Arthritis (Polyarthritis) 06/2022 - 01/2003
68	Fibrosis (Cirrhosis) 01/2022 - 01/2007
39	Systemic Scleroderma (Systemic Sclerosis) 01/2022 - 01/2007
37	Psoriatic Arthritis 08/2022 - 10/2010
25	Bone Resorption 01/2022 - 07/2003
25	Necrosis 01/2022 - 01/2005
19	Psoriasis (Pustulosis Palmaris et Plantaris) 07/2022 - 10/2010
16	COVID-19 12/2022 - 01/2020
16	Systemic Lupus Erythematosus (Libman-Sacks Disease) 07/2022 - 02/2006
16	Osteoarthritis 01/2022 - 07/2010
15	Rheumatic Diseases (Rheumatism) 10/2022 - 05/2008
14	Neoplasms (Cancer) 05/2022 - 05/2011
14	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 02/2006
13	Joint Diseases (Joint Disease) 07/2022 - 07/2007
13	Gout 09/2021 - 04/2010
11	Pain (Aches) 07/2022 - 03/2011
11	Synovitis 06/2022 - 01/2008
11	Experimental Arthritis 05/2021 - 05/2005
10	Infections 01/2022 - 05/2012
9	Osteoporosis 02/2022 - 07/2004
9	Bronchiolitis Obliterans Syndrome 01/2021 - 10/2012
8	Osteophyte 01/2022 - 07/2013
8	Atherosclerosis 10/2020 - 05/2004
7	Vascular Diseases (Vascular Disease) 01/2020 - 12/2005
6	Postmenopausal Osteoporosis 02/2022 - 08/2010
6	Ankylosing Spondylitis 01/2022 - 07/2009
6	Hypoxia (Hypoxemia) 01/2022 - 12/2007
6	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2020 - 08/2008
6	Churg-Strauss Syndrome (Allergic Angiitis) 11/2019 - 02/2009
5	Vasculitis (Vasculitides) 01/2022 - 11/2010
5	Osteitis 11/2021 - 01/2004
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 05/2004
4	Wounds and Injuries (Trauma) 12/2022 - 05/2014
4	Obesity 05/2022 - 02/2015
4	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 03/2021 - 03/2012
4	Type 2 Diabetes Mellitus (MODY) 01/2021 - 07/2012
4	Melanoma (Melanoma, Malignant) 01/2021 - 01/2014
4	Insulin Resistance 01/2021 - 03/2013

Drug/Important Bio-Agent (IBA)

54	CytokinesIBA 01/2022 - 11/2002
45	Bleomycin (Blenoxane)FDA LinkGeneric 01/2022 - 01/2007
41	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2020 - 03/2002
35	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2007
35	AutoantibodiesIBA 10/2022 - 12/2005
28	AntibodiesIBA 10/2022 - 02/2006
26	CollagenIBA 08/2022 - 10/2005
22	Immunoglobulin G (IgG)IBA 01/2022 - 12/2005
19	Biomarkers (Surrogate Marker)IBA 08/2022 - 10/2005
18	Antirheumatic Agents (DMARD)IBA 01/2022 - 06/2005
16	Uric Acid (Urate)IBA 09/2021 - 04/2010
15	InterleukinsIBA 01/2022 - 02/2012
15	LigandsIBA 01/2020 - 11/2006
14	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 05/2012
14	indium-bleomycinIBA 01/2018 - 12/2011
12	Interleukin-17 (Interleukin 17)IBA 05/2022 - 02/2012
12	Biological ProductsIBA 01/2022 - 01/2014
12	Transcription Factors (Transcription Factor)IBA 01/2022 - 12/2009
12	Methotrexate (Mexate)FDA LinkGeneric 10/2021 - 09/2011
12	OsteoprotegerinIBA 01/2018 - 03/2002
11	EnzymesIBA 01/2022 - 11/2010
10	GlucocorticoidsIBA 12/2022 - 03/2013
10	AntigensIBA 01/2021 - 05/2008
10	apremilastIBA 08/2020 - 10/2010
10	Hydroxyproline (4 Hydroxyproline)IBA 03/2016 - 11/2010
9	RNA (Ribonucleic Acid)IBA 07/2022 - 01/2017
9	Interleukin-6 (Interleukin 6)IBA 01/2020 - 01/2015
9	tocilizumab (atlizumab)FDA Link 01/2019 - 05/2012
9	Interleukin-1 (Interleukin 1)IBA 12/2017 - 12/2003
8	DNA (Deoxyribonucleic Acid)IBA 12/2020 - 02/2006
8	ChemokinesIBA 01/2019 - 11/2010
7	Histones (Histone)IBA 12/2022 - 01/2012
7	Monoclonal AntibodiesIBA 08/2022 - 06/2008
7	Messenger RNA (mRNA)IBA 06/2022 - 04/2011
7	secukinumabIBA 01/2022 - 01/2018
7	AutoantigensIBA 02/2017 - 12/2005
6	Rheumatoid FactorIBA 10/2022 - 03/2014
6	Immunoglobulin A (IgA)IBA 01/2022 - 03/2012
6	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2021 - 12/2009
6	C-Reactive ProteinIBA 12/2020 - 12/2006
6	Cathepsin KIBA 01/2016 - 10/2005
5	Glucose (Dextrose)FDA LinkGeneric 05/2022 - 03/2013
5	Interleukin-23 (Interleukin 23)IBA 05/2022 - 09/2015
5	Estrogens (Estrogen)FDA Link 02/2022 - 03/2013
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 05/2009
5	OsteocalcinIBA 08/2021 - 01/2006
5	Pharmaceutical PreparationsIBA 01/2020 - 01/2007
5	Phosphotransferases (Kinase)IBA 01/2020 - 07/2008
5	RANK LigandIBA 06/2013 - 10/2005
5	Imatinib Mesylate (Gleevec)FDA Link 11/2012 - 01/2007
4	guselkumabIBA 08/2022 - 11/2021
4	LipidsIBA 06/2022 - 07/2017
4	Interleukin-33IBA 01/2022 - 04/2011
4	ChromatinIBA 01/2022 - 01/2012
4	Immunoglobulin M (IgM)IBA 01/2022 - 12/2007
4	baricitinibIBA 12/2021 - 09/2018
4	Janus KinasesIBA 12/2021 - 09/2018
4	Rituximab (Mabthera)FDA Link 03/2021 - 05/2012

Therapy/Procedure

69	Therapeutics 07/2022 - 03/2002
8	Ovariectomy (Oophorectomy) 02/2022 - 08/2010